Cultural events in the area are presented through many sources. The Moberly Area Council on the Arts brings top-quality, professional entertainment several times a year, from orchestras, dance troupes, folk musicians, and storytellers to full-scale musicals and ballets. Shows are held at venues throughout Moberly, including the recently renovated historic Municipal Auditorium.

Moberly Area Community College students present plays and concerts throughout the year in their 400-seat Fine Arts Auditorium. The college’s former historic gymnasium has been converted into a gallery that features many special displays from paintings and photography to sculpture and
quilts. The college also holds entertainment events in their state-of-the-art Activity Center. Events in the past have included activities such as trade shows, the circus, Extreme Fighting, the Harlem Globe Trotters, and the Lipizzanner Stallions. Basketball fans will enjoy the exciting games of the Greyhounds and Lady Greyhounds.

Moberly Senior High School has a student-produced musical each November and other plays and concerts during the school year. The High School Jazz band consistently brings home top honors in state-wide competitions.

Central Christian College of the Bible presents an annual musical event, and tours surrounding communities with their talented student groups.

The Randolph County Fair is held every July in Rothwell Park. The fair features 4-H Achievement Days and the 4-H and FFA Livestock Shows. Many displays and fun-filled events are featured next to the carnival’s midway. Other fairs include the Higbee Fair, The Old Settlers Reunion and Fall Fair, and Cairo/Jacksonville Pioneer Day.

Movie buffs will enjoy The Five and Drive Theater at the north edge of the city. It is believed to be the only combination indoor movie theater and drive-in in the nation and is one of only a dozen drive-in theaters still operating in Missouri, and one of only about 400 still in operation in the nation. The Randolph County Historical Society is renovating the historical Fourth Street Theater to be used for small-venue community events.

Moberly Regional Medical Center sponsors the Healthy Woman program, which puts on a health talk every month. Once a year they sponsor a tour which brings in nationally recognized inspirational guest speakers such as Dale Smith Thomas and Ali Vincent.